2021-10-29 09:36Press release

Asgard Therapeutics’ project awarded € 2 million by EUREKA Eurostars

Asgard Therapeutics’ team at the new lab at SmiLe, from left: Fábio Rosa, Cristiana Pires, Filipe Pereira, Lars Hedbys, Gunnar Gårdemyr and Christine Widstrand.Asgard Therapeutics’ team at the new lab at SmiLe, from left: Fábio Rosa, Cristiana Pires, Filipe Pereira, Lars Hedbys, Gunnar Gårdemyr and Christine Widstrand.

SmiLe Incubator company Asgard Therapeutics collaborates with Lund University and two European contract research organizations in the project REPRogramming tumors INTo immune cells: a revolutionary gene therapy to treat cancer. The three-year proposal was ranked #4 out of 644 European applications for "Eurostars Cut-off 15", and is thereby securing a grant of 2 million euros.

REPRogramming tumors INTo immune cells - REPRINT aims to validate Asgard Therapeutics' TrojanDC gene therapy efficacy and safety – using mouse models and custom 3D human culture systems.

Asgard Therapeutics coordinates the collaboration and delivers TrojanDC, a novel gene therapy for hard-to-treat solid tumors. TrojanDC is administered within tumors and employs a unique mode-of-action, in which cancer cells are reprogrammed into dendritic cells, a special type of immune cell that orchestrates potent specific anti-tumor immune responses.

“We are really pleased to start this collaboration and work with a consortium of partners that bring their expertise together to accelerate TrojanDC development. We will be able to demonstrate TrojanDC’s efficacy and safety, and thereby enabling GMP-like production and regulatory filing for first-in-human studies,” says Cristiana Pires, CEO and co-founder of Asgard Therapeutics.

For more information: Cristiana Pires, co-founder and CEO Asgard Therapeutics, +46(0)731 566 072 or cristiana.pires@asgardthx.com

Asgard Therapeutics
was founded in 2018 as a spin-off from Lund University aiming to advance cancer immunotherapies by developing a paradigm-shifting gene therapy – TrojanDC. Driven by the urgent need for new cost-effective immunotherapies consistently effective in a broad range of patients, Asgard is developing the world’s first cancer immunotherapy based on direct cell reprogramming, forcing cancer cells to become immunogenic and unleashing the immune system against cancer. Learn more at asgardthx.com and follow us on Twitter @AsgardThx.

LSCC, Lund University – Lund University Stem Cell Center (LSCC) is one of six Swedish strategic centers of excellence in life sciences. Asgard´s co-founder Dr. Filipe Pereira is head of the Cell Reprogramming in Hematopoiesis Group of the LSCC and considered an influential researcher in the cell reprogramming field with >45 publications, >3,300 citations. Find more at http://www.pereiralab.com/.

EUREKA Eurostars– is a publicly funded intergovernmental network with an aim to foster innovation-driven entrepreneurship in EU between both small and large industries, research institutes and universities. For more information visit https://www.eurekanetwork.org/countries/sweden/eurostars/.



Language: English

About SmiLe Venture Hub – Pioneering Life Science Innovations

SmiLe Incubator is a life science business incubator based in Medicon Village in Lund, Sweden. SmiLe helps entrepreneurs commercialize their ideas. There are currently 25 companies in SmiLe which, together with alumni companies, have attracted more than EUR 460 million in venture capital to date since 2014. SmiLe offers excellent business coaching, a broad international network of contacts and a dynamic community, as well as well-equipped laboratories which is unique of its kind in Sweden. SmiLe is a non-profit organization and receives basic funding from Region Skåne, Lund Municipality, Lund University and Medicon Village. SmiLe´s sponsors are Agilent, Sparbanken Skåne, Awa, Høiberg, Prevas, Setterwalls, Zacco, Aqilion. SmiLe’s listed alumni companies have a market capitalization of EUR 1,3 billion (Q1 2021). www.smileincubator.life