NanoTemper’s ultramodern instrument is now at SmiLe

Prometheus NT.48 from the instrument company NanoTemper, SmiLe’s new Gold Sponsor, provides our companies with even better knowledge about their proteins. The state-of-the-art instrument, which is now in one of SmiLe’s well-equipped laboratories, is a strong complement to the rest of the equipment.

NanoTemper’s Prometheus NT.48 is an important resource for companies that work with proteins or develop biological drugs, a category that is growing worldwide. With the help of the software, the analyses provide answers regarding chemical stability, folding, aggregation, folding kinetics and ligand binding of proteins.

SmiLe Incubator has eleven laboratories with advanced instrumentation and access to experts who are happy to guide the companies. Separate laboratories are available for everything from cell processing, histology and molecular biology studies, to microscopy and chemical and biological analyses. The addition of the Prometheus NT.48 provides SmiLe’s laboratories with yet another advanced instrument for protein analysis. SmiLe welcomes all small and medium enterprises to use the laboratories through Open Lab Skåne.

A company that has used the Prometheus NT.48 at SmiLe is SARomics Biostructures, one of SmiLe’s alumni companies. SARomics Biostructures provides structural biology services to pharmaceutical companies and universities that study proteins. The company also sells high purity crystallization grade drug target recombinant proteins.

“Prometheus provides a completely revolutionary approach to the analysis of membrane proteins and hydrophobic proteins. They can’t be analyzed using our own equipment, which is based on a different analysis method. For us, having access to the Prometheus as an additional analysis method is highly beneficial, especially when our own instrument can’t be used,” says Maria Håkansson, principal scientist and head of the Crystallization team at SARomics Biostructures.

“Access to NanoTemper’s instruments here generates great value for our companies. We want to provide the companies with optimal conditions for success, which in our industry means not just business advice and capital, but also advanced infrastructure. We equip the labs so that companies can start their studies from day one, without having to invest in expensive instruments. We are extremely pleased that instrument suppliers have begun to view SmiLe as an arena in which they can showcase their instruments,” says Ebba Fåhraeus, CEO of SmiLe Incubator.

For more information, please contact:Ebba Fåhraeus, CEO of SmiLe Incubator, +46 (0)73 4000433, ebba@smileincubator.life

Information about Prometheus NT.48:

Prometheus NT.48 allows you to perform an in-depth analysis of your protein/antibody and look at folding, re-folding, aggregation, folding kinetics, and chemical stability. With it, there are several advantages:

• Label-free measurements
• Broad concentration range of 5ug/ml – 250mg/ml
• Low sample consumption
• Measures folding and aggregation in parallel
• Speed (around 30 minutes for up to 48 samples)
• Easy to use
• High data density and reproducibility (around 20 datapoints per minute per Celsius)
• Low running costs
• No maintenance

For more information about Prometheus NT.48, please visit www.nanotempertech.com or contact vinko.misetic@nanotempertech.com

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